SEMINÁRIO ÂMBITO MESTRADO BIOESTATÍSTICA: Doppler Flow Pattern in Patients with Aortic Coarctation

Abstract: 

Patients with coarctation of the aorta (CoAo) often show a Doppler flow pattern with diastolic flow in the descending aorta. The effect of arterial stiffness on CoAo flow pattern was described in-vitro and with computer models. Study of Doppler flow patterns may provide helpful data to support the decision of CoAo. Using regression models, this study aims to describe the relation between Doppler flow pattern, Invasive Gradients and Arterial Stiffness, in patients that underwent angiography in Santa Cruz Hospital, between 2011 and 2015. Fifty studies were obtained in 31 patients (in 19 patients, studies were performed before and after intervention). Systolic invasive gradients were measured to evaluate CoAo severity. Doppler and arterial stiffness parameters were measured at the time of invasive evaluation. Simple and multiple linear and logistic regression models were obtained. Doppler systolic and diastolic parameters correlated well with severity of CoAo. In mild to moderate CoAo, Doppler diastolic flow in the descending aorta was more likely in patients with lower arterial stiffness.